SoECC - Sum of Edge Clustering Coefficient
Definition
SoECC define the sum of edge clustering coefficients of node u as:
where Nu denotes the set of all neighbor nodes of node u. Obviously, SoECC(u)
will be larger if node u that with higher degree. In this sense, SoECC has a
integrated characteristic of edges and nodes.
SoECC is a method for identifying essential proteins based on edge clustering coefficient which binds characteristics of edges and nodes effectively.
Edge Clustering Coefficient
For an edge Eu,v connecting node u and node v, we pay attention to how many other nodes that adjoin both u and v. The edge clustering coefficient of Eu,v can be defined by the following expression:
where zu,v denotes the number of triangles that include the edge actually in the
network, du and dv are degrees of node u and node v, respectively. Then the
meaning of min(du−1, dv−1) is the number of triangles in which the edge Eu,v
may possibly participate at most.

SoECC is a method for identifying essential proteins based on edge clustering coefficient which binds characteristics of edges and nodes effectively.
Edge Clustering Coefficient
For an edge Eu,v connecting node u and node v, we pay attention to how many other nodes that adjoin both u and v. The edge clustering coefficient of Eu,v can be defined by the following expression:

Requirements
Unweighted, undirected network.
Software
References
- WANG, H., LI, M., WANG, J. & PAN, Y. 2011. A New Method for Identifying Essential Proteins Based on Edge Clustering Coefficient. In: CHEN, J., WANG, J. & ZELIKOVSKY, A. (eds.) Bioinformatics Research and Applications. Springer Berlin Heidelberg.
DOI: 10.1007/978-3-642-21260-4_12