SDP - Structurally Dominant Proteins

Based on multivariate statistical analysis through integrating the degree, closeness, betweenness, k-shell, clustering coefficient, semi-local centrality, eigenvector centrality and further considering the appearances of nodes in network motifs, developed a new measure to characterize the structurally dominant proteins (SDP) in PPI networks.

• Wang, P., Yu, X. and Lu, J., 2014. Identification and evolution of structurally dominant nodes in protein-protein interaction networks. IEEE transactions on biomedical circuits and systems, 8(1), pp.87-97. DOI: 10.1109/TBCAS.2014.2303160